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|Total Unspecified Impurity:||0.08%||Individual Unspecified Impurlty:||0.05%|
|Related Compound C:||0.04%||Related Compound D:||0.05%|
|Related Compound E:||0.06%||Limit Of Cyclohexane:||ND|
Anti Estrogen For Breast Cancer Treatment
is the aromatase inhibitor of choice. mechanism of action - blocking conversion of aromatizableto estrogen - is in contrast to the mechanism of action of anti estrogens such as
clomiphene (Clomid) or tamoxifen (Nolvadex), which block estrogen receptors in some tissues, and activate
estrogen receptors in others.
This was the first selective aromatase inhibitor used in bodybuilding, and is still the most popular estrogen control drug. It's commonly available in both tablet and liquid form for oral use. Dosing is typically 0.25, 0.5, or 1.0 mg at a time, at a frequency of once per day or per two days.
Estradiol, the most potent form of estrogen, is produced in the body by aromatization ofn. This occurs via the aromatase enzyme. Because certain levels of estradiol are needed for men, some conversion of to estradiol is required. However, in two circumstances effective aromatase inhibition can give important benefits.
First, when an anabolic cycle causes very aromatizable levels and there is no control of the aromatase enzyme, conversion to estradiol becomes excessive. The resulting high estradiol can cause gynecomastia, water retention, depression, and/or loss of libido. It may also make it difficult to maintain a lean condition.
And second, some men have excessive estradiol levels even when not on an anabolic cycle. This will act to decrease their natural production, and can also cause the above adverse side effects.
CAS No: 313-06-4
Molecular formula: C17H19N5
Molecular weight: 293.37
Appearance: White powder.
Minimum order: 1g
Half life :50 hours
melting point130.14 ¡ãC
water solubility0.5 mg/mL
|Description||White crystalline powder||Complies|
|Identification||IR HPLC Reactive||Conform with standard IR Conform with standard HPLC Conform|
|Solubility||Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile||Complies|
|Total Unspecified Impurity||max. 0.2%||0.08%|
|Individual unspecified impurlty||max. 0.1%||0.05%|
|Related compound B||max. 0.2%||0.07%|
|Related compound C||max. 0.2%||0.04%|
|Related compound D||max. 0.1%||0.05%|
|Related compound E||max. 0.1%||0.06%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.07%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32 .|
CAS No: 120511-73-1
The drug is appropriately used when using substantial amounts of aromatizing , or when one is prone to gynecomastia and using moderate amounts of such does not have the side effects of salivary tests, should be taken after the first week of use to determine if the dosing is correct.
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